Maternal Exposures to Mycotoxins and Adverse Pregnancy Outcomes (MEMAPO)

 

About the project:

While adverse pregnancy outcomes can have many causes, maternal food intake clearly plays an essential role in the development of the baby. One problem is foods with insufficient nutrient content, yet another is foods containing hazardous chemicals, including mycotoxins.

Mycotoxins are toxic compounds naturally produced by certain types of molds (fungi) that often contaminate various foodstuffs, including cereals, dried fruits, nuts, and spices. Examples of major mycotoxins are aflatoxins, fumonisins, ochratoxin A, citrinin, and deoxynivalenol. Mycotoxins are chemically stable and survive common food processing and cooking practices, making them a ubiquitous exposure in many populations, with serious health consequences such as liver cancer. 

The MEMAPO study is an add-on project to the Food and Agricultural Approaches to Reducing Malnutrition (FAARM) cluster-randomized trial, including 2700 women and their children under three years in 96 settlements in Habiganj District, Sylhet Division, Bangladesh. 

The MEMAPO study specifically investigates (i) household knowledge, experience, and practices regarding mold contamination of food crops, (ii) the exposure level of households and pregnant women to mycotoxins, and (iii) the potential role of maternal exposure to multiple mycotoxins for the development of specific adverse pregnancy outcomes – pregnancy loss, babies born too soon or born too small.

Project Leads:

External collaborators:

Main funders:

  • Federal Ministry of Education and Research (BMBF) through FAARM
  • GNPC Foundation Fellowship (2017 – 2020)

Publications:

  • Kyei NNA., Waid JL., Ali N., Gabrysch S.: Awareness, experience, and knowledge of farming households in rural Bangladesh concerning mold and mycotoxin contamination of food crops: a cross-sectional study. Under review at Mycotoxin Research.